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Research Article | Volume 19 Issue 2 (April-June, 2026) | Pages 110 - 115
Elephantiasis Nostras Verrucosa Secondary to Tuberculosis Verrucosa Cutis: A Rare Presentation of Cutaneous Tuberculosis
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1
PG Resident MD Dermatology, Department of Dermatology, Pt. Jawahar Lal Nehru Memorial Medical College, Raipur, Chhattisgarh, India
2
MD Dermatology, Department of Dermatology, Pt. Jawahar Lal Nehru Memorial Medical College, Raipur, Chhattisgarh, IndiaPG ResidentMD Dermatology
Under a Creative Commons license
Open Access
Received
April 25, 2026
Revised
May 1, 2026
Accepted
May 10, 2026
Published
May 21, 2026
Abstract

Elephantiasis nostras verrucosa (ENV) is a rare form of chronic lymphedema, most commonly affecting the lower limbs. It has primary and secondary etiologies; primary lymphedema results from an intrinsic abnormality of the lymph-conducting pathway, while secondary lymphedema—which is more common—results from an acquired obstruction or obliteration of the lymph-conducting pathway. We report a 49-year-old female presenting with a slowly progressive verrucous swelling over the dorsum of the right lower leg for one year, clinically mimicking ENV. Histopathology revealed epithelioid granulomas with Langhans giant cells and caseous necrosis. Cartridge-based nucleic acid amplification testing (CBNAAT) confirmed Mycobacterium tuberculosis without rifampicin resistance, while the interferon-gamma release assay (IGRA) was positive. The patient was started on standard anti-tubercular therapy with early clinical improvement. This report describes a rare case of elephantiasis of the lower limb where the underlying etiology was cutaneous tuberculosis.

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